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KMID : 0351619750160020029
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Kyungpook Medical Journal
1975 Volume.16 No. 2 p.29 ~ p.36
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Effect of Testosterone Durabolin and Prednisolone on Estrogen-Induced Anemia
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Abstract
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This study ~i-as undertaken to assess the hematologial effect of testosterone, du~abolin and prednisolone on estrogen induced anemic rats with the following results.
1. After a period of feu´- wee´ss a significant reduction in both hemoglobin and reticul~cytes was observed in the rats receiving only estradiol benzoate.
2. A concomitant use of estradiol benzoate and te;~tosterone revealed no alteration. in hemoglobin but a marked increase in reticulocytes.
3. A concomitant use of estradiol benzoate and dur~abolin disclosed more remarkable enhancement ´ of hemoglobin, reticulocytes, marrow nucleated red cells as well as erythrocyte o9Fe incorporation , as compared tp the former group.
4. Hematologically, no appreciable difference vas noted between a group with concomitant use ~; ^f estradiol benzoate and prednisolone, and t!~e group receiving only estradiol benzoate.
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KEYWORD
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